Innovative in vitro and in vivo modeling studies led to the development of this active capable of preventing the clinical signs of slight to moderate acne. Produced from the pericarps of pomegranates (Punica granatum) from the orchards of the Tunisian Gabès oasis, it restores the homeostasis of acneic skin by targeting its four principal abnormalities:

• Colonization by C. acnes is limited by reducing bacterial proliferation, quorum sensing activity and biofilm formation;
• Activity of the sebaceous gland is regulated;
• Inflammation is neutralized by limiting keratinocyte sebocyte and lymphocyte inflammatory responses;
• Hyperkeratinization is reduced.

The clinical efficacy of ACNESIUM^® is demonstrated under control by dermatologists in a cohort of adult Caucasian patients suffering from slight to moderate acne. The GEA score (Global evaluation acne) decreases significantly and the number of lesions is reduced. With this care combining rapidity of action and efficacy, the quality of life of patients is improved.

Available in preservative-free powder, ACNESIUM^® (INCI name: Maltodextrin & Punica granatum Pericarp Extract) is perfectly safe for the acneic skin of adults.