A mechanism of action targeting the bacteria causing odors

Among the broad diversity of bacteria of the cutaneous microbiota, certain species stand out by their ability to produce odorous molecules. In particular, this is the case of Staphylococcus hominis.

In order to elucidate the mechanism leading to the generation of odors, SILAB developed an original modeling study that demonstrated quantitative (increased abundance) and qualitative modifications (increased enzymatic activity) of S. hominis strains sampled from the axillary microbiota of malodorous volunteers subjected to physical activity, compared to a non-odorous panel.

In response to this problem, DEOLYA^® limits the excessive abundance of S. hominis in the axillary cutaneous microbiota and targets the enzymatic activity of this bacterial species. The active ingredient thus has a significant action on the source of perspiration odors while leaving the microbial diversity of this skin zone unaffected.

Double performance against odors and axillary irritation

Tested in a Caucasian panel of both sexes participating in a physical activity, DEOLYA^® reduces perspiration odors by 58% as of the first application. This deodorant efficacy, assessed by an olfactory evaluation from an expert panel qualified in sensorial measurement, is confirmed at the molecular level by a significant 76.3% reduction of the malodorous 3M3SH thiol. These effects are also observed after 7 days of daily use and without having applied the deodorant DEOLYA^® in the morning before the physical activity session, underlining the immediate and long-term effect of the deodorant.

At the same time, DEOLYA^® reduces inflammation, thus significantly decreasing the frequency of unpleasant underarm sensations appearance, daily but also after shaving or epilation (after 28 days of use). In addition, the active ingredient strengthens the barrier function, resulting in vivo in an improvement of Transepidermal water loss (TEWL) of underarm skin.

DEOLYA^® is therefore a natural deodorant solution providing comfort and soothing to the axillary zone.

A french, organic-certified supply

For this development, SILAB Research beneficially used the tellimagrandin-type ellagitannins and proanthocyanidols found in meadowsweet, giving DEOLYA^® its unique polyphenolic profile. Obtained from French suppliers certified for organic agriculture and traced back to the harvest site, this raw material complies with SILAB’s criteria for traceability and sustainability.

DEOLYA^® is a patented active ingredient recommended in all deodorant care products at a dose of 0.1 to 1.0%. Available in aqueous solution, it is easy to formulate. It complies with biodiversity regulations and has a natural origin content of 99.2% (ISO 16128). It complies with international cosmetics regulations (Europe, USA, China, Japan, etc.).

Documentation available on the product page (connection to the private part required).