These multi-layer in vitro models, known either as reconstructed epidermises or reconstructed skins, are an essential factor in proving the efficacy of the cosmetic natural active ingredients sold by the company.
The methodology used is robust, and SILAB complies with three levels of requirements: traceability of the biological material, internal control of skills and methods, and the quality and reproducibility of the models. This requires standardized protocols and a suitable environment, combined with state-of-the-art equipment and high-tech analyses such as transcriptomics.
Thanks to this expertise, the SILAB in vitro specialists, who are regularly trained in new technologies, have been able to develop innovative 3D models to accompany the launch of new cosmetic active ingredients, under normal and modified conditions that mimic a specific biological reality (aging, photo-aging, nutritional deficiency, chemical aggression, inflammation, etc.)
This new generation of complex models represents the expected predictive link between in vitro studies on cell mono-layers (keratinocytes, fibroblasts, etc.) and measurements taken in vivo on volunteers.
The company now clearly displays its expertise through its own SILABSKIN® 3D biological models registered trademark. It continues to create new concepts independently, in line with its original strategy of internally developing the latest know-how in its laboratories, for the use of research and its clients.