Genuine booster of the endogenous synthesis of hyaluronic acid and expression of HAS2, PROHYAL+^® is an active ingredient rich in yeast oligosaccharides from blue agave leaves (Metschnikowia agaves). The hydration benefit, the skin microrelief smoothing and the decrease of crow’s feet wrinkles are proven on volunteers. With an efficacy comparable to that of formulated hyaluronic acid, PROHYAL+^® is adapted to all cosmetic anti-aging formulations.